Maximizing Procedures Covering Conduct of Examination in a Potential World Class University using Operational Research Technique

One of the good qualities of a world class university is their high standard examination procedures. This paper attempts to optimize the examination procedures in a potential world class university by minimizing the major variables: time, cost and human resources involved in the examination conduct. Covenant University, the best private university in Nigeria, is used as a case study. The examination procedures covering conduct of examination at Covenant University, were modelled as a linear programming with time, cost and human resources as our decision variables. The constraint, including the nonnegativity constraint, were carefully formed. The standard form of the model is solved using Simplex method with the aid of a computer software - LIP Solver, which was used to evaluate the feasible solutions from the initial tableau. It was observed that some of the decision variables such as time to correct examination questions and address examination misconducts must be deemphasized, while decision variables such as time to admit students into the examination hall and time to verify students’ identity in order to admit them into the examination hall should be given priority in order to optimize the resources related to the examination conduct at Covenant University

Mobile-Bayesian Diagnostic System for Childhood Infectious Diseases

About 5.9 million children under the age of 5 died in 2015, Preterm birth, delivery complications and infections source a great number of neonatal deaths. the Sustainable Development goals (SDGs) 3.2 is to end preventable deaths of newborns and children under 5 years of age, with a target to reduce neonatal mortality to at least 12 per 1,000 live births and under-5 mortality to at least as low as 25 per 1,000 live births in all countries. However quality and accessible healthcare service is essential to achieve this goal whereas most undeveloped and developing countries still have poor access to quality healthcare. with the emergences on mobile computing and telemedicine, this work provide diagnostics alternative for childhood infectious diseases using Naïve Bayesian classier which has been proven to be efficient in handling uncertainty as regards learning of incomplete data. In this research, sample data was collected from hospitals to model a pediatric system using Naïve Bayes classifier, which produce a 70% accuracy level suitable for a decision support system. The model was also integrated into a SMS platform to enable ease of usage

Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge

Structural MRI is widely used for investigating brain atrophy in many neurodegenerative disorders, with several research groups developing and publishing techniques to provide quantitative assessments of this longitudinal change. Often techniques are compared through computation of required sample size estimates for future clinical trials. However interpretation of such comparisons is rendered complex because, despite using the same publicly available cohorts, the various techniques have been assessed with different data exclusions and different statistical analysis models. We created the MIRIAD atrophy challenge in order to test various capabilities of atrophy measurement techniques. The data consisted of 69 subjects (46 Alzheimer's disease, 23 control) who were scanned multiple (up to twelve) times at nine visits over a follow-up period of one to two years, resulting in 708 total image sets. Nine participating groups from 6 countries completed the challenge by providing volumetric measurements of key structures (whole brain, lateral ventricle, left and right hippocampi) for each dataset and atrophy measurements of these structures for each time point pair (both forward and backward) of a given subject. From these results, we formally compared techniques using exactly the same dataset. First, we assessed the repeatability of each technique using rates obtained from short intervals where no measurable atrophy is expected. For those measures that provided direct measures of atrophy between pairs of images, we also assessed symmetry and transitivity. Then, we performed a statistical analysis in a consistent manner using linear mixed effect models. The models, one for repeated measures of volume made at multiple time-points and a second for repeated "direct" measures of change in brain volume, appropriately allowed for the correlation between measures made on the same subject and were shown to fit the data well. From these models, we obtained estimates of the distribution of atrophy rates in the Alzheimer's disease (AD) and control groups and of required sample sizes to detect a 25% treatment effect, in relation to healthy ageing, with 95% significance and 80% power over follow-up periods of 6, 12, and 24months. Uncertainty in these estimates, and head-to-head comparisons between techniques, were carried out using the bootstrap. The lateral ventricles provided the most stable measurements, followed by the brain. The hippocampi had much more variability across participants, likely because of differences in segmentation protocol and less distinct boundaries. Most methods showed no indication of bias based on the short-term interval results, and direct measures provided good consistency in terms of symmetry and transitivity. The resulting annualized rates of change derived from the model ranged from, for whole brain: -1.4% to -2.2% (AD) and -0.35% to -0.67% (control), for ventricles: 4.6% to 10.2% (AD) and 1.2% to 3.4% (control), and for hippocampi: -1.5% to -7.0% (AD) and -0.4% to -1.4% (control). There were large and statistically significant differences in the sample size requirements between many of the techniques. The lowest sample sizes for each of these structures, for a trial with a 12month follow-up period, were 242 (95% CI: 154 to 422) for whole brain, 168 (95% CI: 112 to 282) for ventricles, 190 (95% CI: 146 to 268) for left hippocampi, and 158 (95% CI: 116 to 228) for right hippocampi. This analysis represents one of the most extensive statistical comparisons of a large number of different atrophy measurement techniques from around the globe. The challenge data will remain online and publicly available so that other groups can assess their methods